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Prelude Therapeutics Inc (PRLD) Financial History

20 years of revenue, earnings, cash-flow and balance-sheet history from public filings.

HEALTHCARE · BIOTECHNOLOGY · DATA UPDATED 2026-10-03

Prelude Therapeutics Inc (PRLD) operates in the BIOTECHNOLOGY industry and is headquartered in Wilmington, United States with about 79 employees. Its market capitalization is roughly $309 million. In the fiscal year ended 2025-12-31, PRLD reported $12M in revenue and ($99M) in net income.

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients.

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PRLD Revenue & Earnings History — Annual Income Statement

Income statementTTM → 2026-06-302025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-31
Total Revenue$23M$12M$7M$0M$0M$0M$0M$0M$0M
Gross Profit$22M$10M$7M($1M)($3M)($2M)($1M)$0M$0M
Gross Margin %95.7%85.9%100.0%——————
Operating Income (EBIT)($66M)($105M)($140M)($132M)($124M)($114M)($59M)($28M)($15M)
Operating Margin %-287.0%-861.3%-1995.9%——————
Net Income($60M)($99M)($127M)($122M)($107M)($111M)($57M)($28M)($15M)
Net Margin %-260.9%-819.6%-1816.8%——————
EBITDA($59M)($98M)($125M)($121M)($122M)($113M)($58M)($28M)($15M)
Earnings Per Share (EPS)$-0.79$-1.29$-1.68$-2.02$-2.27$-2.33$-1.30$-0.85$-9.31
Shares Outstanding (M)98M77M76M60M47M48M44M—2M

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRLD Quarterly Revenue & Earnings — Last 8 Quarters

Quarterly income statement2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-30
Total Revenue$6M$5M$6M$6M$0M$0M$4M$3M
Gross Profit$6M$4M$6M$6M$0M$0M$4M$3M
Gross Margin %100.0%91.5%100.0%100.0%——100.0%100.0%
Operating Income (EBIT)($15M)($14M)($17M)($20M)($32M)($35M)($34M)($34M)
Operating Margin %-270.9%-309.5%-307.6%-314.1%——-845.8%-1145.9%
Net Income($14M)($10M)($16M)($20M)($31M)($32M)($29M)($32M)
Net Margin %-244.1%-226.8%-291.8%-303.5%——-718.3%-1075.7%
EBITDA($14M)($10M)($16M)($19M)($31M)($32M)($28M)($32M)
Earnings Per Share (EPS)$-0.14$-0.13$-0.26$-0.26$-0.41$-0.42$-0.38$-0.43
Shares Outstanding (M)98M83M63M76M76M76M76M76M

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRLD Free Cash Flow History

Cash flowTTM → 2026-06-302025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-31
Cash from Operations (CFO)($34M)($56M)($103M)($107M)($84M)($84M)($46M)($26M)($13M)
Capital Expenditures (CapEx)$0M$0M$1M$4M$3M$2M$1M$1M$1M
Free Cash Flow (FCF)($34M)($56M)($104M)($111M)($87M)($86M)($47M)($26M)($13M)
FCF Margin %-147.8%-464.3%-1480.7%——————

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRLD Quarterly Free Cash Flow — Last 8 Quarters

Quarterly cash flow2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-30
Cash from Operations (CFO)($16M)($22M)$23M($19M)($26M)($34M)($21M)($27M)
Capital Expenditures (CapEx)$0M$0M$0M$0M$0M$0M$0M$0M
Free Cash Flow (FCF)($16M)($22M)$23M($19M)($26M)($34M)($21M)($27M)
FCF Margin %-273.0%-473.5%409.9%-294.1%——-519.9%-912.0%

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRLD Balance Sheet History

Balance sheet2026-06-302025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-312018-12-31
Total Assets$189M$141M$176M$278M$220M$305M$224M$22M$16M
Cash & Cash Equivalents$26M$35M$12M$25M$31M$32M$218M$19M$16M
Total Liabilities$56M$73M$44M$41M$25M$19M$11M$71M$39M
Total Debt (Short + Long-Term)$3M$3M$3M$1M$2M$2M$0M$0M$0M
Total Shareholders' Equity$134M$69M$131M$237M$195M$286M$212M($49M)($23M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

Quarterly statements, profitability ratios, price history, insider activity and institutional holders are in the interactive PRLD viewer.

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