20 years of revenue, earnings, cash-flow and balance-sheet history from public filings.
Denali Therapeutics Inc (DNLI) operates in the BIOTECHNOLOGY industry and is headquartered in South San Francisco, United States with about 503 employees. Its market capitalization is roughly $3 billion. In the fiscal year ended 2025-12-31, DNLI reported $0M in revenue and ($513M) in net income.
Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases.
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| Income statement | TTM → 2026-06-30 | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Revenue | $4M | $0M | $0M | $331M | $108M | $49M | $336M | $27M | $129M | $0M | $0M | $0M |
| Gross Profit | ($104M) | ($11M) | ($8M) | $331M | $108M | $49M | $336M | $27M | $129M | ($74M) | ($1M) | $0M |
| Gross Margin % | -2889.8% | — | — | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | — | — | — |
| Operating Income (EBIT) | ($543M) | ($555M) | ($487M) | ($197M) | ($341M) | ($296M) | $63M | ($213M) | ($46M) | ($90M) | ($87M) | ($17M) |
| Operating Margin % | -15058.2% | — | — | -59.5% | -314.2% | -607.8% | 18.7% | -799.1% | -35.9% | — | — | — |
| Net Income | ($511M) | ($513M) | ($423M) | ($145M) | ($326M) | ($291M) | $71M | ($198M) | ($36M) | ($88M) | ($87M) | ($17M) |
| Net Margin % | -14191.2% | — | — | -43.9% | -300.6% | -597.1% | 21.2% | -740.7% | -28.1% | — | — | — |
| EBITDA | ($497M) | ($498M) | ($493M) | ($128M) | ($316M) | ($287M) | $71M | ($205M) | ($39M) | ($87M) | ($86M) | ($15M) |
| Earnings Per Share (EPS) | $-2.84 | $-2.92 | $-2.57 | $-1.06 | $-2.60 | $-2.39 | $0.63 | $-2.07 | $-0.39 | $-5.89 | $-13.49 | $-5.58 |
| Shares Outstanding (M) | 187M | 175M | 164M | 137M | 126M | 122M | 113M | 96M | 93M | 15M | 6M | 3M |
USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).
| Quarterly income statement | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 |
|---|---|---|---|---|---|---|---|---|
| Total Revenue | $4M | $0M | $0M | $0M | $0M | $0M | $0M | $0M |
| Gross Profit | $4M | ($3M) | ($3M) | ($102M) | ($3M) | — | — | — |
| Gross Margin % | 97.4% | — | — | — | — | — | — | — |
| Operating Income (EBIT) | ($131M) | ($137M) | ($137M) | ($137M) | ($135M) | ($146M) | ($130M) | ($123M) |
| Operating Margin % | -3622.1% | — | — | — | — | — | — | — |
| Net Income | ($128M) | ($128M) | ($129M) | ($127M) | ($124M) | ($133M) | ($115M) | ($107M) |
| Net Margin % | -3539.2% | — | — | — | — | — | — | — |
| EBITDA | ($124M) | ($126M) | ($125M) | ($123M) | ($120M) | ($130M) | ($112M) | ($105M) |
| Earnings Per Share (EPS) | $-0.68 | $-0.69 | $-0.73 | $-0.74 | $-0.72 | $-0.78 | $-0.67 | $-0.63 |
| Shares Outstanding (M) | 187M | 187M | 175M | 172M | 171M | 171M | 170M | 169M |
USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).
| Cash flow | TTM → 2026-06-30 | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations (CFO) | ($434M) | ($413M) | ($348M) | ($358M) | ($245M) | ($211M) | $416M | ($152M) | $50M | ($77M) | ($72M) | ($15M) |
| Capital Expenditures (CapEx) | $6M | $10M | $16M | $13M | $18M | $8M | $3M | $18M | $3M | $3M | $6M | $3M |
| Free Cash Flow (FCF) | ($440M) | ($422M) | ($364M) | ($371M) | ($263M) | ($220M) | $413M | ($169M) | $47M | ($80M) | ($78M) | ($18M) |
| FCF Margin % | -12214.6% | — | — | -112.2% | -242.1% | -451.9% | 123.1% | -635.3% | 36.2% | — | — | — |
USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).
| Quarterly cash flow | 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | 2025-03-31 | 2024-12-31 | 2024-09-30 |
|---|---|---|---|---|---|---|---|---|
| Cash from Operations (CFO) | ($97M) | ($131M) | ($99M) | ($107M) | ($75M) | ($131M) | ($84M) | ($59M) |
| Capital Expenditures (CapEx) | $1M | $2M | $2M | $1M | $4M | $5M | $5M | $4M |
| Free Cash Flow (FCF) | ($98M) | ($134M) | ($100M) | ($109M) | ($80M) | ($137M) | ($89M) | ($63M) |
| FCF Margin % | -2713.8% | — | — | — | — | — | — | — |
USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).
| Balance sheet | 2026-06-30 | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | 2020-12-31 | 2019-12-31 | 2018-12-31 | 2017-12-31 | 2016-12-31 | 2015-12-31 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | $1.2B | $1.1B | $1.4B | $1.2B | $1.5B | $1.4B | $1.6B | $553M | $662M | $487M | $271M | $37M |
| Cash & Cash Equivalents | $202M | $205M | $175M | $127M | $218M | $293M | $507M | $79M | $77M | $218M | $40M | $31M |
| Total Liabilities | $323M | $131M | $144M | $123M | $418M | $442M | $454M | $158M | $115M | $21M | $17M | $52M |
| Total Debt (Short + Long-Term) | $0M | $10M | $12M | $7M | $7M | $5M | $5M | $4M | $19M | $0M | $0M | $0M |
| Total Shareholders' Equity | $835M | $1.0B | $1.2B | $1.0B | $1.0B | $962M | $1.2B | $395M | $547M | $466M | $255M | ($16M) |
USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).
Quarterly statements, profitability ratios, price history, insider activity and institutional holders are in the interactive DNLI viewer.
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