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Spyre Therapeutics, Inc. (SYRE) Financial History

4 years of revenue, earnings, cash-flow and balance-sheet history from public filings.

Healthcare · Biotechnology · DATA UPDATED 2026-07-10

Spyre Therapeutics, Inc. (SYRE) operates in the Biotechnology industry and is headquartered in Waltham, United States with about 112 employees. Its market capitalization is roughly $9 billion. In the fiscal year ended 2025-12-31, SYRE reported $0M in revenue and ($155M) in net income.

Spyre Therapeutics, Inc., a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD) and rheumatic diseases.

Interactive charts & full statements →

SYRE Revenue & Earnings History — Annual Income Statement

Income statement2025-12-312024-12-312023-12-312022-12-31
Total Revenue$0M$0M$1M$2M
Operating Income (EBIT)($220M)($209M)($129M)($85M)
Net Income($155M)($208M)($339M)($84M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

SYRE Quarterly Revenue & Earnings — Last 8 Quarters

Quarterly income statement2026-03-312025-12-312025-09-302025-06-302025-03-312024-12-31
Total Revenue$0M$0M$0M$0M$0M
Operating Income (EBIT)($76M)($57M)($57M)($52M)($54M)
Net Income($69M)($62M)($11M)($37M)($45M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

SYRE Free Cash Flow History

SYRE Balance Sheet History

Balance sheet2025-12-312024-12-312023-12-312022-12-312021-12-31
Total Assets$778M$608M$342M$71M
Total Liabilities$62M$91M$158M$21M

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

Quarterly statements, profitability ratios, price history, insider activity and institutional holders are in the interactive SYRE viewer.

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