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Prime Medicine, Inc. Common Stock (PRME) Financial History

20 years of revenue, earnings, cash-flow and balance-sheet history from public filings.

HEALTHCARE · BIOTECHNOLOGY · DATA UPDATED 2026-09-24

Prime Medicine, Inc. Common Stock (PRME) operates in the BIOTECHNOLOGY industry and is headquartered in Cambridge, United States with about 146 employees. Its market capitalization is roughly $825 million. In the fiscal year ended 2025-12-31, PRME reported $5M in revenue and ($201M) in net income.

Prime Medicine, Inc., a biotechnology company, engages in delivering genetic medicines to address the spectrum of diseases by deploying gene editing technology in the United States.

Interactive charts & full statements → Open the PRME valuation workbench →

PRME Revenue & Earnings History — Annual Income Statement

Income statementTTM → 2026-06-302025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-31
Total Revenue$4M$5M$3M$0M$5M$0M$5M—
Gross Profit($42M)($3M)$3M($5M)($12M)($5M)$2M($3M)
Gross Margin %-1025.6%-58.1%100.0%—-230.6%—42.8%—
Operating Income (EBIT)($197M)($208M)($202M)($205M)($117M)($84M)($1M)($2M)
Operating Margin %-4824.9%-4498.1%-6787.4%—-2236.9%—-17.9%—
Net Income($188M)($201M)($196M)($198M)($122M)($165M)($3M)($3M)
Net Margin %-4613.1%-4342.4%-6566.6%—-2338.2%—-65.5%—
EBITDA($180M)($196M)($190M)($187M)($121M)($165M)($1M)($2M)
Earnings Per Share (EPS)$-1.14$-1.35$-1.65$-2.18$-1.25$-1.73$-0.04$-0.03
Shares Outstanding (M)177M149M119M91M97M96M96M96M

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRME Quarterly Revenue & Earnings — Last 8 Quarters

Quarterly income statement2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-30
Total Revenue$1M$1M$1M$1M$1M$1M$2M$0M
Gross Profit$1M($1M)$1M($43M)($1M)$1M$2M$0M
Gross Margin %100.0%-116.8%100.0%-3491.0%-67.2%100.0%100.0%100.0%
Operating Income (EBIT)($43M)($51M)($49M)($54M)($53M)($52M)($44M)($54M)
Operating Margin %-3750.9%-5917.5%-5800.5%-4406.0%-4787.2%-3603.3%-2025.7%-25948.3%
Net Income($42M)($49M)($46M)($51M)($53M)($52M)($42M)($53M)
Net Margin %-3649.0%-5738.6%-5498.7%-4129.1%-4716.7%-3568.8%-1936.6%-25128.2%
EBITDA($40M)($47M)($44M)($49M)($51M)($50M)($41M)($51M)
Earnings Per Share (EPS)$-0.24$-0.28$-0.31$-0.32$-0.41$-0.40$-0.36$-0.44
Shares Outstanding (M)177M177M149M161M129M131M119M120M

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRME Free Cash Flow History

Cash flowTTM → 2026-06-302025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-31
Cash from Operations (CFO)($156M)($163M)($123M)($165M)($132M)($34M)($6M)($1M)
Capital Expenditures (CapEx)$1M$5M$7M$9M$16M$4M$1M$1M
Free Cash Flow (FCF)($157M)($167M)($130M)($174M)($148M)($38M)($6M)($2M)
FCF Margin %-3850.9%-3607.4%-4363.4%—-2839.2%—-118.7%—

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRME Quarterly Free Cash Flow — Last 8 Quarters

Quarterly cash flow2026-06-302026-03-312025-12-312025-09-302025-06-302025-03-312024-12-312024-09-30
Cash from Operations (CFO)($41M)($43M)($37M)($35M)($41M)($49M)$16M($26M)
Capital Expenditures (CapEx)$0M$0M$0M$0M$2M$2M$2M$1M
Free Cash Flow (FCF)($41M)($43M)($38M)($35M)($43M)($51M)$14M($27M)
FCF Margin %-3560.8%-5014.5%-4480.4%-2880.5%-3855.1%-3526.8%662.1%-13009.1%

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

PRME Balance Sheet History

Balance sheet2026-06-302025-12-312024-12-312023-12-312022-12-312021-12-312020-12-312019-12-31
Total Assets$249M$343M$298M$194M$360M$302M$55M$9M
Cash & Cash Equivalents$47M$63M$182M$42M$188M$185M$37M$9M
Total Liabilities$209M$222M$144M$61M$44M$62M$21M$7M
Total Debt (Short + Long-Term)$9M$8M$4M$9M$12M$7M$18M$0M
Total Shareholders' Equity$40M$121M$153M$133M$316M$240M$33M$1M

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

Quarterly statements, profitability ratios, price history, insider activity and institutional holders are in the interactive PRME viewer.

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