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Karyopharm Therapeutics Inc. (KPTI) Financial History

4 years of revenue, earnings, cash-flow and balance-sheet history from public filings.

Healthcare · Biotechnology · DATA UPDATED 2026-07-20

Karyopharm Therapeutics Inc. (KPTI) operates in the Biotechnology industry and is headquartered in Newton, United States with about 228 employees. Its market capitalization is roughly $216 million. In the fiscal year ended 2025-12-31, KPTI reported $146M in revenue and ($196M) in net income.

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States.

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KPTI Revenue & Earnings History — Annual Income Statement

Income statement2025-12-312024-12-312023-12-312022-12-312021-12-31
Total Revenue$146M$145M$146M$157M
Gross Profit$140M$139M$141M$152M
Operating Income (EBIT)($91M)($119M)($130M)($142M)
Net Income($196M)($76M)($143M)($165M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

KPTI Quarterly Revenue & Earnings — Last 8 Quarters

Quarterly income statement2026-03-312025-12-312025-09-302025-06-302025-03-312024-12-31
Total Revenue$35M$34M$44M$38M$30M
Gross Profit$34M$33M$42M$37M$29M
Operating Income (EBIT)($27M)($18M)($15M)($24M)($33M)
Net Income($22M)($102M)($33M)($37M)($24M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

KPTI Free Cash Flow History

KPTI Balance Sheet History

Balance sheet2025-12-312024-12-312023-12-312022-12-312021-12-31
Total Assets$108M$164M$240M$358M
Total Liabilities$401M$350M$377M$375M

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

Quarterly statements, profitability ratios, price history, insider activity and institutional holders are in the interactive KPTI viewer.

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